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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 28.18
Human Site: Y869 Identified Species: 41.33
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 Y869 E A K C A L K Y L I G E L V S
Chimpanzee Pan troglodytes XP_518055 1227 139177 Y862 E A K C A L K Y L I G E L V S
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 Y869 E A K C A L K Y L I G E L V S
Dog Lupus familis XP_549061 1234 139874 Y870 E A K C A L K Y L I G E L V S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 Y870 E A K C A I K Y L V G E L V S
Rat Rattus norvegicus Q7M6Z5 1394 158861 M944 S Q R Q E L E M L E E E L K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Y873 E A K C A L K Y L L G E L V S
Frog Xenopus laevis Q91784 1226 138905 Y871 E A K C A L K Y L I T E L V S
Zebra Danio Brachydanio rerio Q58G59 1363 154819 W962 A K K E A L L W E R S G L E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 N452 L E R E R V E N S K L A A K L
Honey Bee Apis mellifera XP_395595 1064 123475 N726 I M R K E K I N S T N T E K I
Nematode Worm Caenorhab. elegans P46873 699 78760 A367 A V G V G A P A Q D A F S I E
Sea Urchin Strong. purpuratus P46872 699 78679 L367 F Q K E I E E L K K Q I S E S
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 E713 K R L K E L L E A R K S S A R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 N835 T M S P G A R N S R I F A L E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 S596 D A L F E I S S A G D A I P P
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 100 100 N.A. 86.6 26.6 N.A. N.A. 93.3 93.3 33.3 N.A. 0 0 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. N.A. 100 93.3 40 N.A. 20 6.6 6.6 20
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 50 0 0 50 13 0 7 13 0 7 13 13 7 0 % A
% Cys: 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % D
% Glu: 44 7 0 19 25 7 19 7 7 7 7 50 7 13 13 % E
% Phe: 7 0 0 7 0 0 0 0 0 0 0 13 0 0 0 % F
% Gly: 0 0 7 0 13 0 0 0 0 7 38 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 7 13 7 0 0 32 7 7 7 7 7 % I
% Lys: 7 7 57 13 0 7 44 0 7 13 7 0 0 19 7 % K
% Leu: 7 0 13 0 0 57 13 7 50 7 7 0 57 7 7 % L
% Met: 0 13 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 7 0 0 0 0 0 0 7 7 % P
% Gln: 0 13 0 7 0 0 0 0 7 0 7 0 0 0 0 % Q
% Arg: 0 7 19 0 7 0 7 0 0 19 0 0 0 0 7 % R
% Ser: 7 0 7 0 0 0 7 7 19 0 7 7 19 0 57 % S
% Thr: 7 0 0 0 0 0 0 0 0 7 7 7 0 0 0 % T
% Val: 0 7 0 7 0 7 0 0 0 7 0 0 0 44 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _